Dr. Nissan Pilest

Board-Certified Dermatologist by the American Board of Dermatology

Nissan Pilest, M.D. is a board-certified dermatologist dedicated to the art of aesthetic dermatology. He has developed a national reputation with his dermatology practice, treating both medical and cosmetic patients, beginning in 1979.  Dr. Pilest has practiced in Orange County, California for over 38 years.

Dr. Pilest Board-Certified Dermatologist Irvine & Orange County, CA
Dr. Pilest Achievements Irvine CA

2018 DCA Top 100 Doctors’ Award

Dr. Pilest was one out of 100 selected from a field of 6000 nominees for the award. His win is a testimonial to the fact that referring doctors hold him in high esteem.

Top Doctor 2015 & 2016

Selected by the Orange County Medical Association, Dr. Pilest now joins the elite ranks as a Physician of Excellence for 2015 and 2016.

Over a million physicians in the country can inject – only 3% qualify for Expert Injector status.

Dr. Pilest has attained the coveted Circle of Excellence from the American Society of Dermatologic Surgeons.

Known for his extensive experience and superior aesthetic talent, he was named the Dermatologist of the Year by the Consumer Business Review and is the winner of the Doctor’s Choice Award for 2014 and 2015. Additionally, he is listed in the “Best Doctors Book” and is a winner of the Best Dermatologist of Irvine for 2012 and 2014.

Top Doc Orange County Nissan Pilest


Total Dermatology
Based on 176 Reviews
Linda W.
Linda W.
2019-10-22 10:45:43
The whole team at Total Dermatology is exceptional. I just finished seeing Sandy who so kind and professional. She really cleaned up my skin and I left... read more
Suzanne P.
Suzanne P.
2019-10-02 17:32:20
I came in for a dermafushion sandra's was wonderful and nice she explained everything about the procedure. Everything went well. I highly recommend this... read more
Lauren E.
Lauren E.
2019-08-13 23:47:33
Update!!! Just had my semi-annual Botox/restalyne (under-eye filler) and I can't wait to see final results!! Been seeing a lot of my girlfriends go to... read more

*Individuals Results May Vary.

Leading the Way in Cosmetic Dermatology

Dr. Pilest prides himself on staying on top of the latest technologies as well as the newest techniques, remaining on the cutting edge of all aesthetic cosmetic procedures. He knows that “A growing practice demands a growing Doctor.”

Dr. Pilest is an Assistant Clinical Professor at the University of California, Irvine. He was elected President of the Dermatological Society of Orange County in 2012 and is a Fellow of the American Society for Laser Medicine and Surgery.

Training Expertise

Dr. Pilest is also well known in his community for being a Training Physician for injectables and lasers. He is a Physician trainer for Juvederm Voluma, an Allergan Botox/Medicis Dysport Training Physician, Diamond Botox Physician, Diamond Juvederm Physician, Platinum Restylane Physician, and a Radiesse Black Card Expert.

He holds Advanced Certification for Thermage, is a Fraxel Re:Store/Fraxel Re:Pair CO2 Laser Training Physician for Solta Medical Aesthetics and is also a professional speaker for Thermage technology.

Circle of Excellence Member

Named to the Circle of Excellence in Soft Tissue Fillers, inclusion in this prestigious group of physicians represents a special industry recognition of knowledge and ability.

The American Society for Dermatologic Surgery awards this designation to board-certified dermatologists who have demonstrated their knowledge through one of the most rigorous qualifying exams in the industry.

“My patients trust me with their personal appearance and it’s my privilege and duty to be sure I’m amply qualified to do the job as perfectly as possible!”

Circle of Excellence Certification Nissan Pilest, MD

A Caring Doctor

Dr. Pilest routinely donates his time and services to charities that benefit cancer patients, such as the Pediatric Cancer Research Foundation and The Breast Cancer Foundation.  He is married and has two grown children and two grandchildren. He is an avid traveler.

  • Top Scar Removal Doctor
  • Top Juvederm Doctor 2011
  • Top Injectable Fillers Doctor
  • Top Fraxel Laser Doctor
  • 2011 Gold Elite on RealSelf.com
  • Top Restylane Doctor 2011
  • Top Botox Doctor 2011

“Dr. Pilest is the only Doctor I trust to perform any of my injections. I don’t do much but the tweaks here and there are so natural and make me look like a more rested and prettier version of myself. Today I got undereye filler and Xeomin! I love the immediate results of the undereye filler! I will definitely be back for all of my dermatology needs!”
More Patient Reviews

“I couldn’t be happier with my treatments from Dr. Pilest. He always treats me with dignity and compassion and always gives me thoughtful and honest advice and information. I love his staff, too. It’s a busy practice because of their expertise and cutting-edge treatments, but they always take the time to answer any question and address any concern. Best cosmetic dermatologist in OC!”
More Patient Reviews

*Individual Results May Vary


We love our patients at Total Dermatology! Read what our satisfied patients have to say about their experiences with Dr. Pilest and our team.

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*Individual Results May Vary

Memberships and Professional Positions

Take the First Step – Request A Consultation

Schedule your consultation with board-certified dermatologist Dr. Nissan Pilest at Total Dermatology in Irvine, CA today by calling (949) 727-3800

*Individual Results May Vary