Modern aesthetics is moving away from generic, mass-produced gels in favor of personalized, biological solutions. For patients prioritizing ingredient transparency, EZGEL offers the ultimate clarity: a restorative volume treatment created entirely from your own blood. At Total Dermatology, Dr. Nissan Pilest uses this "bio-filler" to bridge the gap between traditional skincare and clinical volume restoration. It’s a truly organic approach to anti-aging.
EZGEL is a next-generation, completely natural injectable gel created from your own body that combines the regenerative power of Platelet-Rich Fibrin (PRF) with a thicker, moldable consistency to act as a dermal filler, providing immediate structure, lift, and long-term collagen stimulation.
| Cost | $1,500 per session; $3,000 for a package of three |
| Downtime | Minimal downtime; 24–48 hours for mild swelling |
| Pain Level | Low; patients experience minimal discomfort with local numbing |
| Duration | Sustained results over several months through collagen production |
Your Biology, Amplified
While people often think of regenerative medicine as thin liquid serums, EZGEL is a versatile, thick concentrate that works well for multiple skin concerns across the face and neck.
Purity in Every Drop
The best part about EZGEL PRF is that it is a natural treatment that works in harmony with your own body.
Assessing Your Potential
EZGEL is a great choice for almost anyone seeking skin rejuvenation, but you do need a healthy biological foundation for the healing process to be effective. This treatment is generally not a good fit for patients with severe platelet dysfunction, chronic liver disease, active systemic infections, or poor overall skin health. Dr. Pilest will turn away patients who have unrealistic expectations for an "instant" surgical result, as EZGEL is a biological repair process that requires healthy lifestyle habits to truly thrive.
The Forty-Minute Refinement
The appointment starts with a blood draw, just like a regular checkup. We then process the blood sample to separate white blood cells and platelets from red blood cells, creating a smooth, moldable gel. The blood draw feels like a quick, tiny "spicy pinch." During the facial treatments, Dr. Pilest or our expert team uses numbing cream so that patients experience minimal discomfort. You mostly feel a sense of "pressure" as the EZGEL is placed to promote tissue regeneration and wrinkle reduction.
Back to Life Tonight
You will generally be ready to get back to your normal routine within 24 to 48 hours, as this is a cosmetic treatment with minimal downtime. You can return to your routine almost immediately, but avoid intense heat exposure or heavy exercise for a day or two. We recommend avoiding blood-thinning medications and other blood-thinning agents like cod liver oil, essential fatty acids, or high doses of vitamin E for one week prior to minimize bruising.
Patience is Key
Patience is key with regenerative medicine because your results rely on a biological timeline. While the gel restores volume right away, you will look slightly "swollen" for about 48 hours before the final, smooth skin tone reveals itself. Because EZGEL triggers natural collagen production, the optimal results are long-lasting. Most patients see their skin elasticity and volume continue to improve for several months as the PRF works beneath the surface.
Invest in Your Biology
The price for EZGEL reflects the specialized technology needed to turn your own blood into a dermal filler. A single session is $1,500, a package of two is $2,400, and a package of three is $3,000. Pricing reflects the customization required for your skin concerns and anatomy, and we offer financing options through Cherry to keep cosmetic procedures accessible.
Beyond the Basic Spa
Dr. Nissan Pilest has been a leader in Orange County dermatology since 1979. While many facilities offer basic PRP treatment or PRP injections, Total Dermatology specializes in the advanced platelet rich fibrin technology required for EZGEL. Dr. Pilest has moved our practice toward PRF EZGEL for under eye rejuvenation because it offers a much safer, more natural bridge for hollowing than traditional dermal fillers. By using your own blood cells, we avoid the risk of late-term swelling often seen with lab-made materials.
Schedule your consultation at (949) 727-3800 or through our Online Booking Link.
While PRP hair restoration and PRP treatment use a liquid format for hair follicles, EZGEL is processed into a thick gel for facial rejuvenation and volume loss.
Yes, the growth factors and white blood cells in platelet rich fibrin are scientifically proven to aid in wound healing and tissue damage repair.
EZGEL is excellent for acne scars because it provides immediate volume to lifted depressed areas while inducing collagen stimulation for long-term skin renewal.
We typically recommend an initial series of three sessions, followed by maintenance treatments every 6–12 months to maintain skin elasticity.
Yes. Since EZGEL uses your own blood, it is safe for all skin types and tones without the risk of pigment changes often associated with some laser treatments.
Most patients handle it very well. We use numbing cream and precise techniques to ensure you only feel minimal pressure during the injections.
You get an immediate lift from the gel itself, but the "biological" results—the new collagen—continue to improve the area for three to six months.
When it comes to your skin and your health, it really is all about what’s best for you. Total Dermatology understands this, which is why we offer versatile treatments with experienced and highly trained aesthetic professionals led by Dr. Nissan Pilest. Your Total Dermatology transformation awaits.
